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Bioinformatics and Computational Biology - Master of Science

Engage in cutting-edge learning with the Master of Science in Bioinformatics and Computational Biology. The MS in Bioinformatics and Computational Biology provides education in the theory and practice of the major current areas in the field including problem contexts, mathematical and statistical foundations, computational approaches, communication, and ethical, privacy and legal considerations. In addition to the fundamentals of bioinformatics and computational biology, the program covers relevant probability and statistics, data structures and algorithms, and machine learning. Students who successfully complete the MS in Bioinformatics and Computational Biology will be able to identify, choose, describe, explain, and apply bioinformatics and computational biology methods to problems in biology and biomedical research. The program is offered through the Science Academy in the College of Computer, Mathematical, and Natural Sciences.

The MS in Bioinformatics and Computational Biology is a 30-credit graduate program designed for working professionals and can be completed in less than two years. Instruction is provided by UMD faculty and experts in the field. The program features instructional delivery through face-to-face instruction at the UMD College Park campus, mostly in the evenings.  

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Fall 2027

International Deadline: February 26, 2027

Domestic Deadline: May 28, 2027

Admission Requirements

Any student applying for admission to a graduate program at the University of Maryland must meet the following minimum admission criteria as established by the Graduate School.

  • Earned a four-year baccalaureate degree from a regionally accredited U.S. institution, or an equivalent degree from a non-U.S. institution.
  • Earned a 3.0 GPA (on a 4.0 scale) in all prior undergraduate and graduate coursework.

General Requirements:

  • Statement of Purpose
  • Transcript(s)
  • TOEFL/IELTS/PTE (international graduate students)

Program-Specific Requirements:

  • Graduate Record Examination (GRE) (optional)
  • CV/Resume
  • Description of research/work experience
  • Prior coursework establishing quantitative ability (including calculus II, linear algebra, statistics, etc.)
  • Education or work experience in biological/biomedical sciences, mathematics, statistics and/or computer science fields
  • Proficiency in programming languages, demonstrated either through prior programming coursework or substantial software development experience

Plan of Study & Courses

The MS in Bioinformatics and Computational Biology is a 30-credit, 10-course, non-thesis graduate program. The program provides education in the theory and practice of the major current areas in the bioinformatics and computational biology fields. Elective courses in the Data Science and Machine Learning programs may also be available.

Sample Plan of Study (Part-time, two 3-credit courses per semester)

Semester 1 (fall)

  • BIOI601 Probability & Statistics (Core)
  • BIOI604  Principles of Molecular Biology, Genetics, and Genomics (Core)

Semester 2 (spring)

  • BIOI605 Data Sources and Data Management in Bioinformatics (Core)
  • BIOI606 Sequence Alignment (Core)

Semester 3 (summer)

  • BIOI Elective

Semester 4 (fall)

  • BIOI610 Genome Annotation (Core)
  • BIOI611 Analysis of Gene Expression Data (Core)

Semester 5 (spring)

  • BIOI602 Principles of Data Science (Core)
  • BIOI607 Data Structures and Algorithms for Bioinformatics (Core)

Semester 6 (summer)

  • no courses

Semester 7 (fall)

  • BIOI603 Principles of Machine Learning (Core)

Sample Plan of Study (Full-time, three 3-credit courses per semester)

Semester 1 (fall)

  • BIOI601 Probability & Statistics (Core)
  • BIOI602 Principles of Data Science (Core)
  • BIOI604 Principles of Molecular Biology, Genetics, and Genomics (Core)

Semester 2 (spring)

  • BIOI605 Data Sources and Data Management in Bioinformatics (Core)
  • BIOI606 Sequence Alignment (Core)
  • BIOI607 Data Structures and Algorithms for Bioinformatics(Core)

Semester 3 (summer)

  • BIOI Elective

Semester 4 (fall)

  • BIOI603 Principles of Machine Learning (Core)
  • BIOI611 Analysis of Gene Expression Data (Core)
  • BIOI610 Genome Annotation (Core)

Electives include: 

BIOI 621: Genome Assembly and Annotation
BIOI 622: Metagenomics Data Analysis

Learn more about the courses

Tuition & Fees

Up-to-date tuition and fee information for the MS in Bioinformatics and Computational Biology.

Program Directors & Instructors

Portrait of Michael Cummings Michael Cummings

Director, Bioinformatics and Computational Biology Master's Program

Portrait of Stephen Altschul Stephen Altschul

Lecturer

Portrait of Volker Briken Volker Briken

Cell Biology & Molecular Genetics Professor

Portrait of Najib M. El-Sayed Najib M. El-Sayed

Cell Biology & Molecular Genetics Professor

Portrait of Leonid Koralov Leonid Koralov

Professor, Mathematics

Portrait of Alejandra Mercado Alejandra Mercado

Associate Director, Master's in Telecommunications Program, Electrical and Computer Engineering

Portrait of Tammy Perrin Tammy Perrin

Lecturer

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